• TRI Princeton

Advances in Skin Science, Measurement and Treatment Course

TRI held the annual Skin Science, Measurement and Treatment Course at the TRI site in October. The two-day, intensive course was designed to get participants quickly up to date with the current state of skin research, skin measurement techniques and claims.

The first section of day 1 covered ‘dry skin and skin moisturization’. K.P. Ananth (University of Cincinnati) gave an excellent review of the aetiology of dry skin and the technologies that have been developed to deal with this problem both from ‘outside-in’ and from ‘inside-out’. Laurie Joseph (Rutgers University) built on this by talking about the causes of other skin conditions, such as eczema, and the processes involved in skin aging.

After the first session, the course kept up the tempo by moving straight into a section on ‘skin assessments’. This was a chance for measurement specialists to share their expertise and experience with the attendees. This section included talks on the measurement of skin hydration (Prof Bob Imhof, Biox Systems), FTIR and Raman analysis of skin (Samuel Gourion-Arsiquaud, TRI) and skin imaging and spectroscopy (Paulo Bargo, J&J).

The final session of the first day focussed on another key area for skin scientists, skin penetration into the skin. We were very lucky to have two world class experts to take us through this area. Prof Bozena Michniak-Kohn (Rutgers University) took us on a whistle-stop tour of all the principles of active delivery into the skin and how her team at Rutgers investigates this. Majella Lane (University College London) then explained how formulation design can be used to optimise skin delivery and how various cosmetic excipients can affect the skin penetration of actives.

The second day of the course picked-up the intensive pace of the first day immediately with some high-quality presentations on skin barrier lipids, skin inflammation and UV skin damage. Apostolos Pappas (J&J) kicked-off with a review of what is known about lipid composition of stratum corneum, sebum and hypodermal lipids and their various essential functions. Michael Southall (J&J) built on this with a very thought-provoking review of skin inflammation and its role in various skin conditions. Finally, Curtis Cole (Sun & Skin Consulting) shared his extensive experience and knowledge in developing and testing sunscreens.

Attendees next got stuck-in to a series of laboratory demonstrations from leading instrument manufacturers. Biox demonstrated their new Epsilon contact imaging system for skin moisture content. Skin Test Equipment demonstrated equipment for microcirculation imaging in the skin and equipment for detailed skin imaging. Perkin-Elmer showed us their diverse catalogue of spectroscopy equipment. Bossa-Nova gave live demos of their new SAMBA Face System, and Remspec Corporation gave us a demonstration of their portable fiber-optic spectroscopy equipment.

The course concluded with an excellent, thought provoking talk by Nava Dayan (Dr Nava Dayan LLC). Nava brought the attendees back to the reality of what is required for skin safety assessments and claim substantiation.

In conclusion, on behalf of the organizing committee at TRI, we thank all our speakers and instrument manufacturers for their enthusiastic and high-quality contributions to the course. We also thank all the attendees for their participation and involvement in the course. It is all much appreciated and made for a special two days.

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